Category: Uncategorized

  • Introducing ESR6

    Introducing ESR6

    Hi, nice to meet you! My name is Andris and in the CONSENSE network, I am known as ESR6.

    I guess it is appropriate to start with my background. I was born and raised in Riga, the capital of Latvia, one of the Baltic States. In short, ever since high school, my whole life revolved around chemistry. To not sound cliché, let me explain.

    Growing up I considered myself a “science kid”. I was really interested in literally anything as long as it sounded “science-y”, let it be looking at onion peel film under the microscope or trying to wrap my head around the angular momentum phenomenon in physics. But my chemistry teacher was the most instrumental in satiating my curiosity and rerouted it into an urge to study chemistry (especially organic chemistry, because who needs the easy way out, right?). You could probably guess where this is going.

    I obtained my bachelor’s and master’s degree in Chemical Engineering from Riga Technical University (RTU), Latvia. There, I received an excellent opportunity to learn about different strategies and synthetic procedures in organic chemistry and, most importantly, got to work (and sometimes tinker) with scary and menacing-looking machines like nucleic magnetic resonance (NMR) spectrometers and high-performance liquid chromatography machines.

    Later in my studies, due to my diligent work (or maybe excessive tinkering with machines, I am still not sure), I was offered a research assistant position at the Institute of Technology of Organic Chemistry at RTU. For the curious little boy in me, it was a wonderful creative outlet to make a bunch of new, previously unknown chemicals that sometimes acted or looked weird. My main scientific focus was the synthesis and analysis of annulated pyrimidine derivatives, such as purines and quinazolines. These compounds are widely studied and used in biochemistry and biology, as some of them, for example, are crucial for life processes or disease/disorder treatment, while others make up our DNA and RNA.

    After finishing my master’s, I wanted to explore possibilities out of my comfort zone and dive into something new. As I have previously worked with the synthesis of DNA/RNA building blocks, it seemed only logical to try “a step higher” – to work with DNA itself. Thanks to CONSENSE, I was able to join Professor Kurt Gothelf’s group at Aarhus University, Denmark. This is a life-changing opportunity to gain experience in the fields of oligonucleotide synthesis, DNA modification, protein conjugation, and all that together applied in biosensor technologies. I am genuinely grateful to be part of the CONSENSE ITN network and privileged to carry the ESR title.

    Let’s say this was a decent introduction on my part. Time to wrap up!

    Hope to see you again!

    Author: Andris Jeminejs

  • Marie Skłodowska-Curie Actions in Action!

    Marie Skłodowska-Curie Actions in Action!

    On the 12th and 13th of July 2022, the ESR9 Livio Miranda participated in the Satellite Event promoted by the Marie Skłodowska-Curie Actions (MSCA). The event took place in Leiden (the Netherlands) and comprised different panels on current and essential topics regarding the MSCA priorities, as well as practical workshops. Below, you can check a few words about this event from Livio:

    “The event started-off with a panel that clearly elucidated the priorities of MSCA for the present and future. The list of priorities includes career development (at all stages of career), equality and gender balance, excellence in all fields of research, as well as cooperation with non-academic world, international broadening and intersectoral collaboration.

    The following panels engaged very fruitful discussions among the speakers and the audience, which was mainly comprised of Early Stage Researchers and Researchers supported by the MSCA. The panel on Science Diplomacy raised awareness on policy approaches to science policy for global cooperation in Research and innovation. It was very interesting that the panelists were very motivated and consolidated researchers that at some point took a career shift for science diplomacy roles, which is critical for evidence-based decisions in all spheres of society. 

    The communication workshop was another great opportunity to learn different tools on how to give a TED-like speech for general audiences. During the workshop, the researchers formed groups in order to think collectively on how to make research topics more appealing and exciting for a general public.

    Other than that, societal-relevant discussions were raised among the panelists and audience, including the awareness of new opportunities for Ukrainian researchers, as well as perspectives on policy approaches to support academic freedom for researchers who are at risk.

    You can find some recorded videos and material at the official satellite event website (EuroScience Open Forum 2022 (ESOF) – MSCA Satellite event – idloom-events). And as an interesting fact: between 2012 and 2020, 12 Nobel Prize winners were either backed by or involved in the Marie Skłodowska Curie Actions.”

    Author: Livio Miranda

  • Introducing ESR7​

    Introducing ESR7​

    Hi there! I’m Emily ESR 7 in the CONSENSE consortium.

    I’m here to introduce a little bit about myself so I’ll dive right into my academic background. In 2020, I obtained a Bachelor of Science in Biochemistry from the University of Southampton. Here, I became interested in the topic of synthetic biology, so I decided to continue my education in this area. In 2021, I graduated with a Master of Research in Systems and Synthetic Biology from Imperial College London. Whilst learning about many different aspects of synthetic biology and its potential uses, I became fascinated by the topic of DNA origami, a technique which allows the delicate folding of DNA. I decided to explore a little more in this field by taking an 8-month long research project which involved using DNA origami nanostructures together with time-resolved cryo-EM. Currently I am pursuing a PhD, still within the field of

    DNA origami, now under the supervision of Professor Kurt Gothelf at Aarhus University within the CONSENSE ITN. My PhD project involves the design and fabrication of DNA nanostructures using DNA origami to create a continuous biosensor to detect small biomolecules which are relevant for illness and disease.

    There are many reasons why I decided not only to pursue a PhD in the field of DNA origami but also specifically within the CONSENSE network. Firstly, I am fascinated by the technique and its potential uses in the future. I hope to be able to use my time to become an expert in the field and advance it further into industrial applications. Secondly, I was interested in the idea of joining an ITN because of all the other opportunities it would provide me during my time as a PhD student. I look forward to the secondments in both an academic and industrial setting as it will allow me to experience another new work environment, further my knowledge in different fields and opens doors for collaboration. Along with the secondments taking place abroad, as well as the biannual CONSENSE conferences, this ITN will allow me to further my international experience and develop other personal traits.

    I am privileged to be a part of the CONSENSE ITN and look forward to seeing myself develop scientifically, professionally, and personally in the next few years. I hope this gives you a little idea about myself!

    Until next time!

    Author: Emily Tsang

  • CONSENSE presents its work worldwide

    CONSENSE presents its work worldwide

    A few weeks ago, Helen Tan, one of the ESRs at the TU/e, presented her research results at the 7th Biosensing Technology Conference in Sitges, Spain. She reported on her recent advances in the methodology of biofunctionalized substrate characterization using techniques, such as atomic force microscopy (AFM), DNA Point Accumulation in Nanoscale Topography (DNA-PAINT), and Biosensing by Particle Motion (BPM).

    “Overall, I would say it was a fruitful trip — I learned a lot, gained a few connections, and at the same time, was able to convey what BPM is about and how I should approach my research question. :)”

    The goal of CONSENSE is to train a new generation of professionals in the field of biosensor technologies. For early-stage researchers, the opportunity of networking and receiving feedback is an essential part of the scientific process. Helen was able to learn a bit more regarding the general biosensing techniques that are being used at the moment. However, she also admits that there are not many technologies for continuous biosensing — the gap that the CONSENSE project addresses quite well.

    Helen is grateful for the opportunity to talk to quite a few people regarding her work — most attendees were really interested in the DNA-PAINT approach, a super-resolution localization microscopy (SMLM) technique, so she received some questions about the working principle.

    We wish Helen the best of luck in her work and hope to hear more about her results in the future!

    Author: Andris Jeminejs

  • Follow the CONSENSE ESRs on social media

    Follow the CONSENSE ESRs on social media

    We have set up social media channels specifically for the CONSENSE project to make it easier for interested audiences to follow the CONSENSE Early Stage Researchers. To find out what we are up to follow us on Twitter or LinkedIn to receive updates.

  • CONSENSE meets in Israel

    CONSENSE meets in Israel

    After five months since the last meeting, the CONSENSE network met up again at The Weizmann Institute of Science (WI) in Israel. Unfortunately, due to travel restrictions the conference took place in a hybrid form so all members of CONSENSE could participate.

    The program commenced with a lecture from Professor Fleishman regarding reliable computational optimization of enzymes and binders. Professor Johnsson then presented the use of semi-synthetic protein sensors and lastly, Professor Gothelf shared his expertise in assays for the quantification of small molecules.

    As all members of CONSENSE come from a wide variety of backgrounds, these lectures open up great opportunities for expanding our knowledge in relevant methods and technologies as well open up chances for collaboration and discussions with other members of the network.

    CONSENSE ESRs in Israel

    As with the first meeting, ESRs then presented an update on their research projects. This was followed by questions, discussions and helpful suggestions from the other members of the network.  One major aim of CONSENSE is to train early-stage students and mold them into a new generation of professional researchers, specializing in the field of biosensing.

    To fulfil this aim, a number of workshops took place during this meeting in Israel, not only to develop scientific skills but also transferrable skills. Firstly, Professor Merkx discussed how to effectively publish research papers into journals; a valuable talk specially aimed at the ESRs who may not have yet published work of their own. Next, Miss Strehler and Miss Ciscato (accelCH) carried out a workshop on science communication and how to successfully target a particular audience. Lastly, Marc Scherer (ESR at WI) organized a workshop which provided an introduction on AlphaFold2, PROSS and FuncLib webservers for use in protein optimization. Although not all students are working with protein optimization, it was an eye-opening workshop and gave insight into the type of work Marc carries out on a daily basis. To complete the scientific program of this conference, the ESRs were given a tour of the laboratory facilities at WI.

    For the next few days during the social program, ESRs explored Jerusalem and Tel-Aviv. We enjoyed seeing the difference in culture, architecture and landscapes, and enjoyed the hot weather before returning to Europe. This conference was a fantastic scientific and cultural experience!

    Thank you, Marc, for organizing this unforgettable trip. Until next time!

    Authors: Emily Tsang and Claudia Scarpellini

  • 1st CONSENSE Week

    1st CONSENSE Week

    The first CONSENSE Week is taking place from 25-30 April 2022 in Rehovot, Israel. The event is hosted by CONSENSE beneficiary WI. Organised in a hybrid format, the ESRs will receive training on various scientific and transferable skills, as well as provide a presentation to the network about the progress of their individual research projects.

  • CONSENSE meets for the first time in the Netherlands!

    CONSENSE meets for the first time in the Netherlands!

    The first meeting of CONSENSE has taken place in a hybrid form to allow everyone to join despite the Covid-19 pandemic. Being the first meeting of the consortium, Professor Prins gave a short introduction regarding the principles behind an International Training Network (ITN) and the aims of CONSENSE.

    The program continued with three lectures about the challenges in different areas relevant for our projects in continuous biosensing. The first one was given by Professor De Jonge regarding clinical patient monitoring. The main take-away of this lecture was to underline two areas where continuous biosensing is crucial: in the intensive care unit (ICU) to provide a prompt intervention and in diseases requiring a personalized treatment, for example those occurring with a dysregulated response to infection. For the second lecture, Professor Merkx focused on nanoswitches, highlighting the state-of-the-art and reminding the most important requirements for a continuous biosensor. Lastly, a lecture regarding optical detection technologies, that is the readout method chosen for the CONSENSE project, was held by Professor Lammertyn.

    CONSENSE ESRs in Netherlands

    After, each of the ESRs introduced themselves and their respective projects, typically including the previous work done by the research group and the main concept to develop during their PhD. Each presentation was followed by questions and suggestions coming from all the people involved: other ESRs, PIs or members of the partner organizations. The opportunity to have feedback from people belonging to different backgrounds and experiences is a part of what makes ITNs so special because it allows the researchers involved to grow, develop scientific criticism and find ways of collaborating.

    The scientific program was then concluded with a tour of the laboratory facilities at TU/e, which was particularly interesting to foresee collaboration opportunities and possible secondments.

    The social activities during the CONSENSE introduction days was the first opportunity for the ESRs to get to know each other. The PhD students working at the host institution typically organize some activities to have fun together and we have to say that the ESRs from Tu/e really did a great job! Among the several activities, we visited the Philips Museum with the special guide of a passionate former employee and we had a day trip to Den Bosch. There, we walked around the city, hometown of the painter Bosch until we reached a cafeteria, where we participated in a workshop and had the chance to decorate the typical dessert of the city disguised in the funniest way.

    Many thanks to Anna, Helen, Livio and Sebastian (ESRs at TU/e) for organizing this fantastic introductory meeting. We are looking forward to the next conference in early 2022!

    Authors: Claudia Scarpellini and Emily Tsang

  • CONSENSE Introduction Days

    On 24-25 November 2021, the CONSENSE ITN has its first in-person meeting since the start of the project. Hosted by the CONSENSE coordinator TU Eindhoven, this will be an opportunity for the early-stage researchers to have a broad introduction into the CONSENSE project and to get to know their fellow researchers across the different partnering universities and companies involved.

    During the two-day event, ESRs and supervisors will be following a number of lectures on biosensing technology, and the different ESRs will present their research projects to the rest of the network. In addition, visits will be planned to the biosensor labs at TU Eindhoven.

  • Open Positions for Innovative Training Network CONSENSE!

    Open Positions for Innovative Training Network CONSENSE!

    Are you interested in joining the CONSENSE team as a early stage researcher (ESR)?

    Two beneficiaries have open positions at the moment. Find out more about the individual open positions and how to apply. We are looking forward to receiving your application!